Citation: Raghavan PR (2018) Metadichol® and CD34 Expression in. Improving Longevity with Metadichol® by Inhibiting the BCAT1 Gene PR Raghavan Nanorx Inc, PO Box 131, Chappaqua, NY 10514, USA * Corresponding author: PR Raghavan, Nanorx Inc, PO Box 131, Chappaqua, NY 10514, USA, E-mail: raghavan@nanorxinc. It is made in Switzerland with highest standard to ensure. Metadichol acts as an inverse ag-onist on Nuclear Vitamin D receptors (VDR) that have a ubiquitous presence in cells and. Nano Soma also reduces inflammation and pain of the joints and muscles. Metadichol ® is nanoemulsion of long-chain lipid alcohols derived from food ingredients. Citation: Raghavan PR (2018) Metadichol® and CD34 Expression in. e half the size of a human virus) with all natural ingredients. It is a safe, natural Vitamin C and Vitamin D substitute required for a young vibrant and disease-free helathy leving life style. Type 2 Diabetes paper 3. Metadichol acts on nuclear vitamin D receptors (VDR) (US Patent 9,006,292) that are present in cells throughout the body to stimulate the. It is a liquid formulation that has unique properties Metadichol is a unique Small Molecule Technology Formula (SMTF) ( with a size of 53 nanometers i. Because Metadichol® is made with natural ingredients and has no toxic effects, it can be safely tested humans for its prevention and treatment of many infectious diseases. The open-label study showed Metadichol ® raised levels of vitamin C by 3 fold. This means that, in the presence of NANO SOMA, your body is resourced to produce what it needs to sustain ideal health – whether it’s healthy genes, cells and DNA, or strong. NANO SOMA Liquid (EU patent 2398476 Metadichol®) is a nanoemulsion policosanol, which is found in many foods. Ingredients: Water, Vitamin E TPGS, Policosanols, Preservative (Potassium sorbate), Acidity Regulator (Citric Acid), Emulsifier (Sucrose Esters of Fatty Acids) Please understand that neither the companies supplying any of the Metadichol-based products nor the companies’ directors nor shareholders are medical doctors and do not provide medical. Metadichol®, a nanolipid emulsion of long-chain alcohols, has been demonstrated as a strong candidate that inhibits the proliferation of SARS-CoV-2. Metadichol®: A Novel ROR Gamma Inverse Agonist and Its Applications in Psoriasis. WebMetadichol® is a Nanoemulsion of long-chain alcohols found in many foods. involves a mixture of two liquids, such as water in oil or oil in water droplets. €1,728. Possible mechanisms for the increased Vitamin C levels through antioxidant pathways are presented. 70 (10%) Availability: In stock. Metadichol ® is a Nanoemulsion in water and has a particle size of less than 60 nm. Metadichol® is a nanoformulation of long-chain alcohols that in Zucker diabetic rats and humans has been shown to increases Vitamin C levels above and beyond what is achieved orally [1-3]. NANO SOMA, aka Metadichol is effective for different issues, like Hypertension, Liver problem, TB (Tuberculosis), Diabetes, and others. Note that it has been shown that Metadichol prompts the body to promote healthy aging. involves a mixture of two liquids, such as water in oil or oil in water droplets. Raghavan, the patented formula in NANO SOMA (Metadichol) represents an innovative modern. Subsequently, a Metadichol-containing medium was added to predesignated wells. 48 μg/ml. Summary Metadichol is a safe food-based ingredient in Nano form that has unique uses in many diseases which are impacted by Vitamin C levels . Contact. A61K47/00 — Medicinal preparations characterised by the non-active ingredients used, e. WebPlant-based nano emulsion dietary supplement that come from natural sources and ingredients. Research shows that Metadichol® has the potential to inhibit MDR-TB and XDR-TB. Cell treatments. 247 Metadichol 4. This makes sialidases an interesting target to control pathogenic activity. 91 times in concentration ranges of 1. Any small molecule that can elevate Klotho can, in principle, help reverse many diseases. Metadichol was serially diluted using eight half-log dilutions in test medium (MEM supplemented with 2% FBS and 50 µg/mL gentamicin) so that the starting (high) test concentration was 100 µg/ml. Its constituents are food ingredients that are free of toxic, mutagenic, or teratogenic properties [2,3]. Our patented spray formula improves energy and strengthens the immune system. WebMetadichol can promote synthesis of nicotinamide mononucleotide (NMN) NMN is the direct precursor of NAD+ (nicotinamide adenine dinucleotide) which has been regarded as an emerging ingredient for anti-aging in recent years. The signs and symptoms of a healing crisis are often identical to the illness itself. in other species but not in humans and primates. Thus, it is necessary to develop a universal approach to halt the spread of new and unknown viruses as they are discovered. Metadichol® Patents Metadichol® Approved Patent Claims Metadichol® Published Articles. Conclusion: Metadichol is a safe and effective inhibitor for enveloped viruses in humans. It is manufactured using nano-technology in an FDA approved facility in Switzerland. Europe PMC is an archive of life sciences journal literature. The policosanol is removed in the refining process for sugar, rice and other. This life-supporting nutrient is usually lost during food processing. health and longevity of the nematodes improved when BCAT1 was inhibited, and this gene is inhibited, the amino acid chains accumulated in the tissue triggering longevity in the Nematodes. However, many people in the market are selling policosanol which does not have the same effect on the human system. Metadichol is a safe, noncytotoxic product. Metasomer Topical Gel (US patent 8,722,093 Metadichol®) is a nanoemulsion of long-chain alcohols found in many foods. Dengue & Ebola 4. Metadichol’s nanoparticles of less than 60nm — smaller than a virus — quickly travel throughout the body. Ingredients: Policosanol. It is known that active ingredients in many cleaning agents, wipes and tissues target the influenza envelope and render the virion ineffective. Additionally, vitamin C plays a critical role in cell reprogramming by mitigating ROS effects, which can increase. 11 1 Comment Like CommentMetadichol® is a Nanoemulsion of long-chain alcohols found in many foods. . 16 µg/ml. We now report that Metadichol raised Vitamin C levels by 3 to 4 folds without any diet restrictions as was the case in the hydroxytyrosol study. You save: AU$. Hs683 U87MG Hs683 U87MG. Devotees worship jaggery and immerse it in the temple pond that is believed to cure 4448 diseases. Metadichol® is a nano emulsion that is thought to act via vitamin D receptors to influence the immune system. Different concentrations of Metadichol (1 pg/mL, 100 pg/mL, 1 ng/ml, and 100 ng/mL) were prepared in a serum-free medium. R. Dr. Gradually heat and stir, just until the butter melts. Metadichol acts on multiple genes and has over 2000 unique gene interactions, thereby resulting in a network that brings about homeostasis and prevents SARS-CoV-2 infections. Devotees worship jaggery and immerse it in the temple pond that is believed to cure 4448 diseases. Further a live virus assay in Caco2 cells, Metadichol® inhibited SARS-CoV-2 replication with an EC90 of 0. This food ingredient is found in many foods. Metadichol® is a lipid formulation of long-chain alco-hols, containing C26, C28 (more than 80%), and C30 [14]. The holy grail of immune system support, our patented spray formula improves energy and strengthens immunity. Immune System. Metadichol®, a nano lipid emulsion, has been examined and shown to be a strong candidate to help stop the proliferation of SARS-COV-2. More Info. In rats, it has an LD50 of 5000 mg/kilo and its ingredients are present in many foods we consume on a daily basis. METASOMER Telomerase Natural Skin Cream is made from natural ingredients. It is a safe, natural Vitamin C and Vitamin DActive ingredients 8 in a number of cleaning agents, wipes, and tissues target the viral lipid envelope to render the virions nonviable. Several were proposed as detergent. Klotho levels are low or non-existent in cancer patients. It’s active ingredients are commonly called Policosanols. The key ingredient (US patents 8,722,093, 9,006,292 and 9,034,383 Metadichol®) is a nanoemulsion of long-chain alcohols found in many foods. It’s active ingredients are commonly called Policosanols. doi:10. 661 7. This unique property allows for the use of Metadichol as an immune modulator to prevent future occurrence of SARS- COV–2 and possibly other infections being predicted, facilitating a. Active ingredients. Its mechanism of action is through its binding to the vitamin D receptor (VDR) as an inverse agonist [5]. Take it daily without experiencing any side effects. NANO SOMA® Liquid - 3 Pack. WebAs shown by Q-RT-PCR and validated by Western blot, Metadichol, a nano-emulsion natural lipid alcohol treated Umbilical cord cells, Fibroblasts, cells expressed all of the nuclear receptors at concentrations ranging from 1 picogram per ml to 100 nanogram per ml in a concentration-dependent manner. 8,722,093, 9,006,292 and 9,034,383 Metadichol) is natural and safe immune system support for your body, helping it to restore its optimal biological functions. a U. Metadichol is a nanoemulsion of. examples of Metadichol’s action in increasing Vitamin C levels over and beyond what is achieved by supplementing with 500 mg or multi grams of Vitamin C. A case study of a patient who had acquired MRSA infections and how Metadichol® by its actions on the VDR has resolved the problem of this deadly disease without any side effects is presented. Nano Soma è un sottoinsieme specifico di policosanoli naturali in acqua ultrapura. Given this, we have packaged a 90 day supply at a discount. 001). The primary ingredients in NANO SOMA ™ are Policosanol from rice wax, vitamin E, and water. The work presented here shows that Metadichol® is an inverse agonist of THRA (Thyroid Receptor Alpha) and THRB (Thyroid Receptor Beta). It is commonly called policosanol and is present in unrefined foods such as rice, sugar cane and wheat. Disclaimer: While we work to ensure that product information is correct, on occasion manufacturers may alter their ingredient lists. The key ingredient (US patents 8,722,093, 9,006,292 and 9,034,383 Metadichol®) is a nanoemulsion of long-chain alcohols found in many foods. 91 times in concentration ranges of 1. Furthe rmor e, active ingredients in. This food is the only. Jaggery contains the constituents of NANO SOMA. Metadichol vs Diabetes. It is commonly called policosanol and is present in unrefined foods such as rice, sugar cane and wheat. le s s t han 60 n an om e t e rs (n m ), which is half t he s iz e of a hu m an v iru s . The gene, GULO, that we all carry converts glucose to Vitamin C. Metadichol ist ein weitverbreitetes patentierte Nanoemulsion langkettiger Alkohole, bekannt als policosanol – eine natürliche Substanz, die bei der Raffination aus unserer Nahrung entfernt wird. Metadichol ® is a nano lipid formulation of long-chain alcohols [14]. It has the same efficacy as the NANO SOMA oral spray and is much more practical for topical use. With a size of 60nm, this naturally occurring plant wax, and long chain lipid alcohols, will deliver energy to cells. This paper deals with Metadichol® expression on UCB cells leading to increased CD33 expression similarThe present invention provides the method for the method and treatment disease of regulation and control physiology and metabolizing parameters, this method is applied via to the subject for having this regulation and control and/or treatment needs Come carry out. non toxic and safe as it is a food ingredient that we consume on a daily basis) 9. . It can also prompt fibroblast cells to create nuclear receptors where there were. Generic Name Methacholine DrugBank Accession Number DB06709 Background. . Furthe rmor e, active ingredients in cleaning. List price: AU$267. WebNEW YORK – Metadichol®, a Nano emulsion of a food based ingredient is an immune system booster created by Nanorx Inc. METADICHOL® is a functional food developed by Dr Palayakotai Raghavan ( Dr. It is commonly called Policosanol and is present in foods. Its main ingredient is policosanol that can be found in raw foods such as rice, sugar cane, wheat and peanuts. Ingredients: Water, Vitamin E TPGS, Policosanols, Preservative (Potassium sorbate), Acidity Regulator (Citric Acid), Emulsifier (Sucrose Esters of Fatty Acids) Please understand that neither the companies supplying any of the Metadichol-based products nor the companies’ directors nor shareholders are medical doctors and do not provide medical. Metadichol®, a nano lipid formulation of long-chain alcohols, has been shown to inhibit TMPRSS2 (EC50 96 ng/ml). ingredient of Metadichol in no n-nano form, is totally inactive. Compared to the. NEW YORK – Metadichol®, a Nano emulsion of a food based ingredient is an immune system booster created by Nanorx Inc. After 24 h, the cell monolayer was rinsed with a serum-free medium and treated with Metadichol at predetermined concentrations. The key ingredient (US patents 8,722,093, 9,006,292 and 9,034,383 Metadichol®) is a nanoemulsion of long-chain alcohols found in many foods. patents 8,722,093, 9,034,383 and 9,006,292), also marketed as Nano Soma ® and Nano-. It is a natural, non-toxic food product that has no known side effects. Many people have reported amazing benefits from using the METASOMER Topical Gel, which can be found here. Homo sapiens cannot produce vitamin C like many other species thatthat Metadichol has anti-oxidant and anti-inflammatory properties. Metadichol increases endogenous vitamin C levels, leading to the efficient reprogramming of. Previous studies have demonstrated that Metadichol®. Metadichol ® is nanoemulsion of long-chain lipid alcohols derived from food ingredients. Its constituents are food ingredients that are free of toxic, mutagenic, or teratogenic properties [2,3]. immunity towards that goal we developed Metadichol ® [1]. It is a safe, natural Vitamin C and Vitamin D Metadichol®: A natural nano lipid emulsion that expresses all 48 Nuclear receptors in the Stem, Somatic, and Cancer cells. Ingredients: Water, Vitamin E TPGS, Policosanols, Preservative (Potassium sorbate), Acidity Regulator (Citric Acid), Emulsifier (Sucrose Esters of Fatty Acids) Please understand that neither the companies supplying any of the Metadichol-based products nor the companies’ directors nor shareholders are medical doctors and do not provide medical. Metadichol® A Novel Inverse Agonist of Thyroid Receptor and its Applications in Thyroid DiseasesMetadichol is a Nanoemulsion of long-chain lipid alcohols (C-26, C-28, and C-30), which are commonly known as Policosanols and it binds to VDR and which has been shown to have a role in hypertension. METASOMER Topical Gel is for topical application. 6, 8. *. Metadichol®, a Nano emulsion of food-based ingredient, created by Nanorx Inc. The open-label study showed Metadichol ® raised levels of vitamin C by 3 fold, endogenously without supplementation of Vitamin C. Policosanol. 1, 1, 100, 1000 ng/ml test solutions. | Find, read and cite all the. First, it binds to vitamin D receptors, or VDR, which help regulate glutathione production. It is commonly called Policosanol and is present in foods such as rice, sugar cane, wheat, and peanuts. S. WebIC50 µM IC50 µg/ml Given the increasing importance of BCAT1 in human diseases, Metadichol 3. Metadichol has the potential to be an anti-inflammatory molecule with a broad spectrum of activity. This plant-based, five-ingredient emulsion containing nano policosanol delivers a safe, revolutionary method of helping the body to restore key biological functions. Metadichol is a safe, non-toxic product, made from renewable sources and commercially available for the last six years, with no reported side effects. It is commonly called policosanol and is present in. P R Raghavan, an Inventor of NANO SOMA. It is manufactured using nano-technology in an FDA approved facility in Switzerland. 48 μg/ml. After more than ten years of effort, in 2008, he discovered Metadichol, the primary ingredient in the NANO SOMA line of products. Metadichol. In addition to increased Vitamin C levels reduction in Potassium and uric acid, and decreased blood pressure. United Kingdom. NANO SOMA, (formerly Metadichol®) is an all-natural dietary/food supplement containing the most advanced form of policosanol. METASOMER Telomerase Natural Skin Cream is made from natural ingredients. Its key ingredient, Metadichol, has been shown to regulate all 48/9 nuclear receptors in the. Raghavan sought to discover a smarter, natural alternative: a food-based solution made with a few powerful ingredients without side effects. examples of Metadichol’s action in increasing Vitamin C levels over and beyond what is achieved by supplementing with 500 mg or multi grams of Vitamin C. It holds the body together. Metadichol ® is derived from food-based ingredients. Il segreto unico di NANO SOMA è trasformare il. Abstract and Figures. Citation: Raghavan ®PR (2018) Metadichol and Healthy Skin: One Approach many Possible Cures. Sunday, 13 August 2023 05:40 GMT. , 0. From the Table, it is seen that Metadichol® is 3000 more potent (in µM units) than Gabapentin. The knockdown of tumor suppressor genes, such as p53, enhances reprogramming efficiency (35, 36). We recently showed that [4,5] Metadichol exhibits potent, broad spectrum viral inhibitor y activity in Vero and MDCK cells infected with Dengue,Metadichol ® is a nano formulation of long-chain lipid alcohols derived from food It is a inverse agonist of Vitamin D receptor (VDR), Aryl hydrocarbon receptor (AHR), and ROR gamma (RORC) that. Metadichol’s 81 action on multiple genes and proteins lead to over 2000 unique interactions with other genes and resulting in a network that affects many biomarkers and diseases, thereby ie w r e. Enter the email address you signed up with and we'll email you a reset link. WebNANO SOMA® Australian patents AU 2010216337 and AU 2014235779 Metadichol® is a nanoemulsion of policosanol And it is a revolution for your health Are you looking for a simple all-natural and powerful tool to support your body in a whole new way?. Metadichol by activating the VDRMetasomer Topical Gel (US patents 8,722,093, 9,006,292 and 9,034,383 Metadichol®) is a nanoemulsion of long-chain alcohols found in many foods and is commonly called policosanol and is present in unrefined foods such as rice and sugar cane. Metadichol® [1] is a Nanoemulsion of long-chain alcohols found in many foods. Questa nano-emulsione di policosanolo, una sostanza derivata da. This makes sialidases an interesting target to control pathogenic activity. 00. Metadichol’s nanoparticles of less than 60nm — smaller than a virus — quickly travel throughout the. Metadichol was tested for its inhibitory actions against ACE2 , ACE ( Angiotensin-converting enzyme) , and TMPRSS2 and in an antiviral assay with SARS-COV-2.